What is the Origin of Neural Growth Factors?

The identification of these factors arose from developmental neuroscience, studying how neurons find their targets and survive postnatally. Their relevance to hormonal health stems from the fact that many hormones, including sex steroids and IGF-1, regulate the transcription and secretion of these critical neurotrophins. We look to optimize their endogenous production.

What is the Mechanism of Neural Growth Factors?

Neural Growth Factors operate by binding to specific receptor tyrosine kinases on the neuronal surface, triggering intracellular cascades that promote gene expression related to synaptic strength and neuronal survival. For example, optimal testosterone levels can positively influence BDNF expression, thereby supporting the structural underpinning for learning and memory consolidation. This action directly impacts long-term cognitive architecture.

Neural Growth Factors ∞ Area

Neural Growth Factors

Meaning

Neural Growth Factors are signaling proteins, or neurotrophins, such as Brain-Derived Neurotrophic Factor (BDNF) and Nerve Growth Factor (NGF), that are essential for the survival, differentiation, and maintenance of neurons throughout the lifespan. Their presence supports neuroplasticity, allowing the brain to adapt and form new synaptic connections in response to experience or intervention. These factors are foundational to cognitive health.