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Neural Energy Flux

Meaning

Neural Energy Flux refers to the rate and stability of energy substrate transfer, utilization, and waste clearance within the central nervous system, a process acutely sensitive to the dynamic shifts in hormonal and metabolic status. The brain, being a highly metabolically active organ, relies on a constant, precise flux of glucose, oxygen, and in some states, ketones, to maintain optimal neuronal firing and cognitive function. Compromised Neural Energy Flux, often a consequence of insulin resistance or chronic stress-induced cortisol dysregulation, can manifest clinically as ‘brain fog,’ impaired memory, and diminished executive function. Optimizing this flux is a primary goal in neuro-endocrine health to support sustained cognitive resilience and neuroplasticity.