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Neural Cell Adhesion

Meaning

Neural cell adhesion refers to the complex process by which nerve cells and glial cells physically bind to each other and to the extracellular matrix, a process mediated by specialized cell adhesion molecules (CAMs). This precise physical interaction is fundamental for the proper formation, structural maintenance, and functional connectivity of the nervous system. Adhesion molecules play a crucial role in neurite outgrowth, synaptic formation, and the guidance of migrating neurons during development. Impaired adhesion contributes to neurological dysfunction and reduced synaptic plasticity.