A strategic, proactive approach to maintaining the total functional capacity and structural integrity of the brain and nervous system throughout the lifespan. This involves protecting existing neurons and synapses from damage, supporting glial cell function, and maximizing the potential for neuroplasticity and neurogenesis. Preserving this capital is the fundamental objective of longevity-focused neurological health protocols.
Origin
This term is a conceptual metaphor that likens the finite and valuable resource of the nervous system to ‘Capital,’ which must be preserved and invested in. It draws from neuroscience and the growing clinical focus on preventing age-related cognitive decline rather than merely treating its symptoms.
Mechanism
Preservation is physiologically driven by managing oxidative stress, mitigating chronic inflammation (neuroinflammation), and ensuring a consistent supply of neurotrophic factors, such as BDNF. Hormonal balance, particularly the protective effects of estrogens and androgens on neuronal survival, is a key component. Lifestyle factors like consistent physical activity and cognitive engagement also promote the structural resilience that defines preserved neural capital.
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