Skip to main content

Neoplastic Transformation

Meaning

Neoplastic Transformation is the pathological process by which normal cells acquire the necessary genetic and epigenetic alterations to become neoplastic, leading to uncontrolled proliferation and the formation of a tumor or neoplasm. This transformation involves sequential changes that allow cells to evade growth suppressors, resist apoptosis, and sustain proliferative signaling, representing the initial stage of cancer development. In the context of hormonal health, certain hormone imbalances can act as powerful promoters of this transformation in hormone-sensitive tissues.