Near Infrared (NIR) refers to electromagnetic radiation with wavelengths longer than visible red light but shorter than mid-infrared, typically spanning 700 to 1000 nanometers. In clinical application, NIR light is used therapeutically due to its ability to penetrate tissues and interact with cytochrome c oxidase in the mitochondria. This interaction is crucial for cellular energy modulation.
Origin
The designation “Near Infrared” simply places this spectrum adjacent to the visible red end of the electromagnetic spectrum. Its clinical relevance stems from photobiomodulation research, where specific wavelengths are identified to trigger beneficial cellular responses. It is a physical parameter used to influence biology.
Mechanism
The primary mechanism involves NIR photons being absorbed by chromophores, most notably cytochrome c oxidase within Complex IV of the respiratory chain. This absorption leads to the release of nitric oxide (NO) from the enzyme, which in turn increases the proton gradient and enhances ATP synthesis efficiency. This non-thermal stimulation effectively boosts cellular energetic capacity.
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