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Natriuresis

Meaning

Natriuresis is the physiological process of increased sodium excretion in the urine, primarily driven by hormonal and neural mechanisms to regulate blood volume and blood pressure. This essential renal function is a key homeostatic counter-regulatory mechanism to the body’s sodium-retaining systems. The magnitude of natriuresis directly correlates with the body’s need to eliminate excess fluid and salt, which helps prevent the development of hypertension and volume overload. This process is a fundamental target for pharmaceutical agents aimed at managing cardiovascular and renal health.