What is the Origin of NAD+ Enhancement?

NAD+ is a ubiquitous molecule fundamental to redox reactions in biochemistry, with its enhancement strategy arising from recent advances in aging and metabolism research. The focus on enhancement reflects the observed decline in NAD+ pools with advancing age or chronic metabolic stress. It positions NAD+ as a target for promoting cellular vitality.

What is the Mechanism of NAD+ Enhancement?

Enhancement strategies typically involve supplying precursors like Nicotinamide Riboside (NR) or Nicotinamide Mononucleotide (NMN), which the salvage pathway converts into NAD+. Increased availability supports critical enzymatic functions, notably those involved in DNA repair (PARPs) and energy production within the electron transport chain. This ultimately supports genomic stability and cellular resilience.

NAD+ Enhancement

Meaning

NAD+ Enhancement refers to therapeutic strategies designed to increase the intracellular concentration of Nicotinamide Adenine Dinucleotide (NAD+), a critical coenzyme essential for numerous cellular processes. Elevated NAD+ levels are linked to improved sirtuin activity and enhanced mitochondrial bioenergetics. This intervention is central to protocols aiming to bolster cellular repair and energy metabolism. We seek to restore this vital cofactor to optimal functional levels.