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N-Acetylcysteine

Meaning

N-Acetylcysteine (NAC) is a pharmaceutical and nutraceutical agent, specifically an acetylated derivative of the semi-essential amino acid L-cysteine, primarily recognized for its potent antioxidant and mucolytic properties. Clinically, it serves as a critical, life-saving antidote for acute acetaminophen overdose and is commonly used to break down thick mucus secretions in chronic respiratory conditions. Physiologically, NAC acts as a direct, highly bioavailable precursor to L-cysteine, which is the rate-limiting substrate for the synthesis of glutathione, the body’s master endogenous tripeptide antioxidant. Its utility in hormonal health and wellness is directly linked to its capacity to mitigate systemic oxidative stress and support hepatic detoxification pathways.