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Myokine Activity

Meaning

Myokine Activity refers to the endocrine, paracrine, and/or autocrine signaling function of myokines, which are small peptides released by skeletal muscle fibers in direct response to muscle contraction, primarily during structured exercise. These potent signaling molecules exert diverse and systemic effects on distant organs, including the liver, adipose tissue, bone, and brain, effectively mediating the profound systemic benefits of physical activity. They play a crucial role in regulating glucose metabolism, improving lipid profiles, and suppressing chronic inflammation. Maximizing myokine release is a primary biological objective of all exercise-based hormonal health and metabolic programs.