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Myofibrillar Remodeling

Meaning

Myofibrillar Remodeling is the adaptive physiological process involving the structural alteration, renewal, and precise organization of myofibrils, the fundamental contractile apparatus within skeletal muscle fibers, in response to mechanical tension and metabolic cues. This remodeling includes the net synthesis of new contractile proteins, primarily actin and myosin, leading to an increase in myofibril size and density, which translates directly into enhanced muscle strength and power output. This is the molecular foundation of muscle hypertrophy and functional adaptation to exercise.