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Myocardial Repolarization

Meaning

Myocardial Repolarization is the crucial electrophysiological process in which the heart muscle cells (myocytes) restore their resting negative electrical potential following a depolarization and contraction. This is achieved by the precise efflux of potassium ions (K+) from the cell, which terminates the action potential and prepares the myocyte for the next electrical impulse. Optimal repolarization is essential for maintaining a stable heart rhythm and preventing life-threatening ventricular arrhythmias. This process is highly sensitive to electrolyte balance and the regulatory effects of thyroid and sex hormones.