Muscle Mass Increase signifies a positive net protein balance leading to the accretion of lean body mass, primarily through the enlargement of existing muscle fibers, a process known as hypertrophy. This physiological adaptation is a key objective in managing sarcopenia and optimizing physical performance metrics. Quantifiable increases are typically assessed via dual-energy X-ray absorptiometry or MRI.
Origin
This is a descriptive term combining the physical component, Muscle Mass, with the direction of change, Increase, indicating growth beyond baseline maintenance levels. It is a functional outcome metric in physiology.
Mechanism
The mechanism is driven by anabolism, where the rate of muscle protein synthesis exceeds the rate of muscle protein breakdown. This state is strongly promoted by mechanical tension (resistance training) synergizing with anabolic endocrine signals, most notably the action of insulin and the potentiation provided by sufficient circulating androgens.
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