What is the Origin of Muscle Endocrine?

This concept emerged from modern endocrinology and exercise physiology, challenging the traditional view of muscle as merely a tissue for movement and nutrient storage. The discovery of myokines established the muscle's role as an active communicator, bridging physical activity with systemic health outcomes. This area of study is foundational to understanding the protective effects of exercise against chronic metabolic diseases.

What is the Mechanism of Muscle Endocrine?

Upon contraction, muscle fibers release myokines, such as Irisin and Interleukin-6 (IL-6), which travel through the circulation to influence the function of other organs, including the liver, adipose tissue, and brain. Irisin, for example, promotes fat browning and energy expenditure, while other myokines can modulate inflammation and glucose uptake. Therefore, maintaining muscle health through physical activity is a direct way to support the body's overall endocrine homeostasis.

Muscle Endocrine

Meaning

Muscle Endocrine refers to the recognition of skeletal muscle as a dynamic endocrine organ, capable of synthesizing and secreting various signaling molecules known as myokines, which exert autocrine, paracrine, and endocrine effects on distant tissues. This paradigm shift acknowledges that muscle mass and contraction are not solely mechanical processes but are critical regulators of systemic metabolism, inflammation, and hormonal balance. The health and activity of the muscle endocrine system are paramount for longevity and metabolic resilience.