What is the Origin of Muscle-Centric Longevity?

This is a contemporary concept emerging from gerontology and exercise science, shifting the focus from purely disease avoidance to proactive maintenance of physical performance capacity. It emphasizes muscle tissue as a keystone structure for systemic vitality.

What is the Mechanism of Muscle-Centric Longevity?

Skeletal muscle health directly influences systemic metabolism through glucose disposal and the secretion of myokines, which have systemic effects. Robust muscle tissue supports anabolic hormone sensitivity and provides the physical reserve necessary to withstand physiological stressors. Therefore, strategies maximizing muscle protein synthesis and minimizing muscle fiber atrophy are considered direct mechanisms for enhancing longevity outcomes.

Muscle-Centric Longevity ∞ Area

Muscle-Centric Longevity

Meaning

Muscle-Centric Longevity posits that the maintenance of high-quality skeletal muscle mass and strength is a primary determinant and predictor of overall healthspan and functional independence in later life. This framework prioritizes anabolic signaling, neuromuscular integrity, and mitigating sarcopenia as central goals for extending years of vigorous health. It views muscle as a critical endocrine organ influencing systemic metabolic health.