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mTOR Signaling

Meaning

mTOR Signaling refers to the intricate intracellular pathway governed by the mammalian Target of Rapamycin (mTOR), a serine/threonine protein kinase that acts as a master cellular energy and nutrient sensor. This pathway integrates signals from growth factors, amino acids, and cellular energy status to regulate two fundamental cellular processes: anabolism (growth and protein synthesis) and catabolism (autophagy). The delicate balance of mTOR activity is crucial for muscle hypertrophy, tissue repair, and immune function, but chronic over-activation is implicated in metabolic diseases and accelerated aging. Modulating this pathway is a key strategy in longevity and performance optimization.