What is the Origin of Movement as Medicine?

This phrase is an adaptation of the ancient Hippocratic tenet regarding the healing power of nature, updated with modern exercise physiology and endocrinology. The concept gained clinical traction with the realization that muscle tissue acts as an endocrine organ, secreting myokines. The term emphasizes the therapeutic, prescriptive nature of exercise, elevating it from general wellness to a targeted, evidence-based intervention.

What is the Mechanism of Movement as Medicine?

Movement acts as a powerful endocrine modulator by increasing insulin sensitivity in muscle and adipose tissue, which improves glucose disposal and reduces systemic hyperinsulinemia. Resistance training stimulates the release of anabolic hormones like growth hormone and testosterone, promoting tissue repair and muscle protein synthesis. Furthermore, exercise induces the secretion of myokines, such as Interleukin-6 and irisin, which exert anti-inflammatory effects and promote beneficial metabolic changes in distant organs, including the brain and liver.

Movement as Medicine

Meaning

The clinical paradigm that systematically prescribes specific types, durations, and intensities of physical activity as a primary therapeutic intervention to induce measurable, positive physiological and hormonal adaptations. This approach views structured movement as a potent, dose-dependent stimulus capable of modulating endocrine signaling, improving metabolic health, and enhancing mental well-being. It is a fundamental, non-pharmacological strategy for preventing and managing chronic disease states.