Question 1

What is the Meaning of Mounjaro?

Accepted Answer

Mounjaro is the brand name for the prescription injectable medication tirzepatide, a novel pharmaceutical agent classified as a dual glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist. It is clinically indicated for the treatment of type 2 diabetes mellitus, primarily by improving glycemic control. Due to its potent effects on appetite regulation and metabolic function, it is also associated with significant, dose-dependent weight reduction.

Question 2

What is the Origin of Mounjaro?

Accepted Answer

The medication's active ingredient, tirzepatide, is a synthetic peptide engineered to mimic the action of two naturally occurring human incretin hormones, GIP and GLP-1. Its development stems from decades of research into the enteroendocrine system and the critical role of gut hormones in glucose homeostasis and energy balance. The brand name, Mounjaro, is a commercial designation for the approved therapeutic product.

Question 3

What is the Mechanism of Mounjaro?

Accepted Answer

Mounjaro functions by simultaneously activating both the GIP and GLP-1 receptors in the body, which are found in the pancreas, brain, and gut. This dual agonism enhances glucose-dependent insulin secretion from pancreatic beta cells, thereby lowering blood sugar levels. Furthermore, the drug slows gastric emptying, which contributes to increased satiety, and acts on central nervous system receptors to reduce appetite and food intake, leading to sustained energy deficit and clinically meaningful weight loss.

Mounjaro

Meaning

Origin

Mechanism

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