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MOTS-c Peptide

Meaning

MOTS-c Peptide (Mitochondrial ORF of the 12S rRNA type-c) is a small, biologically active peptide encoded within the mitochondrial genome that acts as a novel, crucial regulator of metabolic homeostasis and systemic insulin sensitivity. This mitochondrial-derived peptide is considered a significant factor in cellular signaling, influencing the body’s response to metabolic stress and potentially extending the healthspan. It is a recent focus in longevity research due to its systemic effects on energy metabolism and cellular resilience.