A class of fatty acids characterized by having one double bond in their molecular structure, such as oleic acid found abundantly in olive oil and avocados. These fats are typically liquid at room temperature and are considered beneficial for cardiovascular and metabolic health when replacing saturated or trans fats in the diet. They are essential dietary components that directly influence cellular membrane fluidity and inflammatory status.
Origin
The term is derived from the chemical structure: ‘mono’ meaning one, ‘un-saturated’ referring to the presence of a double bond that allows for the addition of hydrogen atoms. Nutritional science in the late 20th century highlighted the cardioprotective benefits of these fats, distinguishing them from saturated and polyunsaturated varieties. Their importance is now universally recognized in clinical nutrition guidelines.
Mechanism
Monounsaturated fats are incorporated into the phospholipid bilayers of cell membranes, which can improve insulin receptor function and overall cellular signaling efficiency. Their consumption contributes to a favorable plasma lipid profile by lowering low-density lipoprotein (LDL) cholesterol levels without reducing beneficial high-density lipoprotein (HDL) cholesterol. This metabolic effect helps mitigate the risk of insulin resistance and vascular endothelial dysfunction, supporting hormonal health.
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