Molecular Repair Agents are endogenous or exogenous compounds, often micronutrients or specialized peptides, that directly support the cellular machinery responsible for correcting damage to DNA, proteins, and organelles, such as mitochondria. These agents are critical for counteracting the accumulation of molecular damage associated with aging and metabolic stress. They are the tools for cellular maintenance.
Origin
This concept is derived from molecular biology and the study of aging pathways, specifically focusing on pathways like DNA repair mechanisms and autophagy regulation. In wellness science, it highlights specific molecules that bolster these innate defense systems. These agents are often cofactors in crucial enzymatic reactions.
Mechanism
These agents function by serving as necessary substrates or cofactors for DNA polymerase enzymes, enhancing antioxidant defense systems like glutathione, or upregulating sirtuin activity which governs cellular stress response. By supporting these pathways, they directly reduce the accumulation of molecular entropy that impairs cellular signaling and hormonal receptor function. Their efficacy is measured by improved cellular turnover and reduced oxidative burden.
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