What is the Origin of Molecular Longevity Targets?

This terminology is central to the field of molecular gerontology, where researchers dissect the fundamental biological processes underpinning senescence. The "target" designation implies an actionable point for pharmaceutical or nutritional intervention within the longevity pathway. It signifies a shift from symptom management to upstream biological control.

What is the Mechanism of Molecular Longevity Targets?

Modulation involves upregulating protective mechanisms, such as enhancing AMPK activity to mimic caloric restriction effects or inhibiting pathways that promote protein aggregation. Correcting endocrine signaling, which often declines with age, serves as a critical upstream mechanism supporting these molecular targets. Successful targeting promotes cellular resilience against accumulated damage.

Molecular Longevity Targets

Meaning

Specific cellular pathways, genetic regulators, or biochemical markers identified as key drivers of the aging process that can be therapeutically modulated to extend healthspan. These targets often include sirtuins, mTOR signaling components, or pathways related to DNA repair and epigenetic regulation. We are aiming interventions at the root causes of cellular decay.