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Molecular Longevity Mechanisms

Meaning

Molecular Longevity Mechanisms are the fundamental intracellular and biochemical pathways that precisely govern the rate of cellular aging, efficient repair, and long-term survival across the entire lifespan. These mechanisms include robust DNA repair processes, telomere maintenance, the activity of sirtuin proteins, critical nutrient sensing pathways like the mechanistic Target of Rapamycin (mTOR) and AMP-activated protein kinase (AMPK), and the process of autophagy. Optimizing the function of these conserved pathways is the central scientific strategy for extending healthspan and significantly reducing the incidence of age-related disease. Clinical research focuses on pharmacological and targeted lifestyle interventions that positively modulate these deep biological processes.