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Molecular Integrity

Meaning

Molecular integrity refers to the uncompromised, native chemical structure and functional three-dimensional conformation of all biological macromolecules, including DNA, RNA, proteins, and circulating hormones, which is absolutely essential for their correct physiological role. Maintaining this integrity ensures that cellular components can perform their precise functions, such as accurate genetic transcription, high-affinity receptor binding, and efficient enzymatic catalysis. The progressive loss of molecular integrity, often through cumulative oxidative damage or structural denaturation, is a recognized hallmark of cellular aging and chronic disease pathology.