Molecular Communication Systems represent the intricate and comprehensive network of signaling molecules, including hormones, cytokines, neurotransmitters, and growth factors, that facilitate information exchange between cells, tissues, and distant organ systems. These sophisticated systems are the biological foundation for physiological integration, governing processes from immune surveillance to complex endocrine feedback loops. Maintaining the precision and balance of these systemic signals is essential for optimal health and resilience.
Origin
This broad term unifies the study of various biological signaling pathways, encompassing the traditional fields of endocrinology, neurobiology, and immunology into a systems-level view. It emphasizes the collective, systemic nature of chemical signaling that coordinates whole-body function beyond the scope of any single hormone or molecule.
Mechanism
Communication is achieved through highly specific ligand-receptor binding, where a signaling molecule binds to its corresponding receptor on the target cell surface or inside the cell, initiating an intracellular signal transduction cascade. This cascade typically involves second messengers and protein phosphorylation events, ultimately leading to a change in cellular function, modulation of gene expression, or the release of a subsequent signaling molecule.
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