The Molecular Communication Matrix describes the entirety of interacting signaling molecules—including hormones, cytokines, and neurotransmitters—that govern physiological crosstalk between different organ systems and cells within the body. It represents the complex web of information exchange essential for maintaining systemic equilibrium. Understanding this matrix is key to deciphering complex health states.
Origin
This is a conceptual framework originating from systems biology, visualizing the interconnectedness of the endocrine, immune, and nervous systems as a dynamic signaling network. It moves beyond linear pathways to encompass the simultaneous, multi-modal nature of biological signaling. It frames hormonal influence within a broader context.
Mechanism
Operationally, the matrix functions through feedback loops where the output of one signaling pathway becomes an input for another, exemplified by the interaction between glucocorticoids and insulin signaling. For instance, the presence of specific circulating fractions dictates receptor availability elsewhere in the matrix. Optimization requires ensuring that these molecular messages are transmitted clearly across the entire system.
We use cookies to personalize content and marketing, and to analyze our traffic. This helps us maintain the quality of our free resources. manage your preferences below.
Detailed Cookie Preferences
This helps support our free resources through personalized marketing efforts and promotions.
Analytics cookies help us understand how visitors interact with our website, improving user experience and website performance.
Personalization cookies enable us to customize the content and features of our site based on your interactions, offering a more tailored experience.