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Molecular Command Signaling

Meaning

Molecular Command Signaling refers to the hierarchical and directive communication pathways within a cell or organism, where specific, powerful molecules act as primary messengers to initiate a broad, coordinated, and systemic change in cellular function or overall physiology. These command signals, often involving major hormones or master transcription factors, override lesser, localized signals to dictate a fundamental shift in metabolic state or global gene expression. This powerful signaling is crucial for large-scale, essential adaptations, such as the integrated stress response or deep nutrient sensing.