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Molecular Biology of Motivation

Meaning

The Molecular Biology of Motivation is the study of the genetic, epigenetic, and biochemical signaling pathways that underpin the drive, incentive, and sustained behavioral output required to pursue rewards and achieve goals. This field specifically investigates the role of transcription factors, receptor dynamics, and neuropeptide expression in regulating the brain’s mesolimbic dopamine system. Understanding these molecular mechanisms provides targets for clinical interventions aimed at enhancing intrinsic drive and overcoming apathy.