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Molecular Aging Mechanisms

Meaning

Molecular Aging Mechanisms encompass the fundamental, cellular-level processes that drive biological senescence, tissue dysfunction, and the accumulation of damage over time, ultimately leading to age-related disease. These mechanisms include genomic instability, telomere attrition, epigenetic alterations, loss of proteostasis, mitochondrial dysfunction, cellular senescence, and altered intercellular communication. Understanding these core pathways is essential for developing targeted interventions aimed at extending healthspan.