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Modified Peptides

Meaning

Modified peptides are short chains of amino acids that have been chemically altered post-synthesis to enhance their therapeutic properties, stability, bioavailability, or target specificity. These structural modifications, such as cyclization, amidation, or lipidation, aim to overcome the inherent limitations of native peptides, including rapid enzymatic degradation and poor membrane permeability. In clinical endocrinology, modified peptides are engineered to mimic or modulate the action of naturally occurring hormones and growth factors. They represent a significant advancement in targeted pharmacological intervention for various metabolic and hormonal disorders.