Mitochondrial Support Peptides are a class of short amino acid chains designed to specifically target and enhance the function, integrity, and biogenesis of mitochondria, the cellular organelles responsible for generating cellular energy (ATP). These peptides are employed clinically to improve cellular energy status, enhance metabolic flexibility, and mitigate oxidative stress damage, a key driver of aging. Their therapeutic application is centered on combating age-related decline and chronic diseases associated with primary or secondary mitochondrial dysfunction. They represent a targeted, molecular approach to cellular longevity and resilience.
Origin
This field emerged from the growing, in-depth understanding of mitochondrial involvement in aging and disease, coupled with recent advances in peptide synthesis and targeted delivery systems. The term “Support Peptides” refers to their structural role as signaling molecules that influence and sustain mitochondrial health and function. This therapeutic strategy is rooted in biogerontology and molecular endocrinology research, focusing on endogenous regulatory pathways.
Mechanism
These peptides, such as Humanin or MOTS-c, often act as signaling molecules that enter the mitochondria or influence their communication with the nucleus. Their mechanism includes promoting healthy mitochondrial fusion and fission dynamics, enhancing the efficiency of the electron transport chain, and stimulating the creation of new mitochondria (mitochondrial biogenesis). This targeted action improves ATP output, reduces the generation of damaging reactive oxygen species, and enhances cellular resilience.
We use cookies to personalize content and marketing, and to analyze our traffic. This helps us maintain the quality of our free resources. manage your preferences below.
Detailed Cookie Preferences
This helps support our free resources through personalized marketing efforts and promotions.
Analytics cookies help us understand how visitors interact with our website, improving user experience and website performance.
Personalization cookies enable us to customize the content and features of our site based on your interactions, offering a more tailored experience.