A therapeutic strategy aimed at optimizing the function of the mitochondria, the cellular organelles responsible for producing over 90% of the body’s energy (ATP). Support involves interventions designed to enhance the efficiency of the electron transport chain, promote mitochondrial biogenesis (the creation of new mitochondria), and mitigate the production of damaging reactive oxygen species (ROS). This is a core pillar of longevity medicine, as mitochondrial dysfunction is central to aging and metabolic disease. It directly impacts systemic vitality and energy levels.
Origin
The term is derived from “Mitochondria,” from the Greek mitos (thread) and khondrion (granule), referring to their appearance, and “Efficiency,” signifying optimal operation. “Support” emphasizes the clinical goal of bolstering this critical cellular system. The concept is rooted in the field of cellular bioenergetics.
Mechanism
Support mechanisms include providing essential co-factors, such as CoQ10, L-Carnitine, and specific B vitamins, which are crucial for the various steps of the Krebs cycle and oxidative phosphorylation. Furthermore, activating signaling pathways like AMPK and Sirtuins, often through caloric restriction mimetics or exercise, promotes the clearance of damaged mitochondria (mitophagy) and the creation of new, healthy ones (biogenesis). This dual action maximizes the cell’s energy output and minimizes metabolic waste.
We use cookies to personalize content and marketing, and to analyze our traffic. This helps us maintain the quality of our free resources. manage your preferences below.
Detailed Cookie Preferences
This helps support our free resources through personalized marketing efforts and promotions.
Analytics cookies help us understand how visitors interact with our website, improving user experience and website performance.
Personalization cookies enable us to customize the content and features of our site based on your interactions, offering a more tailored experience.