Mitochondrial Dynamics Control is the regulatory oversight of mitochondrial fusion and fission events essential for maintaining organelle quality and functional integrity.
Origin
This concept is central to modern cellular biology, recognizing that mitochondria are not static but constantly remodeling entities.
Mechanism
Control operates via specialized GTPases like OPA1 and Mfn1/2 for fusion, and Drp1 for fission; optimal balance ensures efficient oxidative phosphorylation and timely mitophagy.
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