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Mitochondrial Bioenergetics Brain

Meaning

Mitochondrial Bioenergetics in the Brain refers to the specialized study and optimization of energy conversion processes within the neurons and glia of the central nervous system, primarily focusing on the function of mitochondria. Given the brain’s immense energy demands, efficient mitochondrial respiration is critical for neurotransmitter synthesis, synaptic transmission, and the maintenance of the energetic gradient required for neuroendocrine signaling. Impairment in these bioenergetics is strongly implicated in cognitive decline, mood disorders, and the pathology of various neurodegenerative conditions.