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Mid-Life Metabolic Shift

Meaning

Mid-life metabolic shift refers to the constellation of physiological and hormonal changes that typically occur around the fourth and fifth decades of life, characterized by a progressive reduction in resting metabolic rate and a tendency toward central adiposity and insulin resistance. This transition is driven by declining sex hormone levels, alterations in growth hormone secretion, and a less favorable body composition. Recognizing this shift is crucial for implementing proactive strategies to mitigate age-related metabolic decline and maintain vitality.