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Microbiome Modulation

Meaning

Microbiome Modulation is the deliberate and targeted alteration of the composition, diversity, and functional activity of the vast community of microorganisms residing within the human gastrointestinal tract, often referred to as the gut microbiota. This clinical strategy aims to shift the balance of microbial species to favor those that produce beneficial metabolites, such as short-chain fatty acids, which profoundly influence systemic health, immune function, and neuroendocrine signaling. A healthy, diverse microbiome is crucial for maintaining the integrity of the gut barrier, reducing chronic systemic inflammation, and regulating the bidirectional communication of the gut-brain axis. Effective modulation is a cornerstone of comprehensive hormonal health management.