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Microbial Metabolite Therapeutics

Meaning

Microbial Metabolite Therapeutics is an innovative class of interventions that utilize specific chemical compounds produced by the gut microbiota to confer therapeutic benefits to the host. These bioactive compounds, often referred to as postbiotics, include short-chain fatty acids (SCFAs) like butyrate, various organic acids, and neurotransmitter precursors. The therapeutic strategy involves administering these isolated or synthesized metabolites directly, bypassing the need for colonization by live bacteria. This approach offers a highly precise, dose-dependent method to modulate host physiology, particularly beneficial for metabolic and hormonal health.