Skip to main content

MI DCI Ratio

Meaning

The MI DCI Ratio represents the critical balance between two inositol stereoisomers, myo-inositol (MI) and D-chiro-inositol (DCI), which function as essential second messengers in the insulin signaling cascade. This ratio is of particular clinical significance in the field of reproductive endocrinology, specifically in the pathophysiology and management of Polycystic Ovary Syndrome (PCOS). Maintaining the correct physiological ratio, typically around 40:1 in healthy follicular fluid, is paramount for optimal ovarian function, glucose metabolism, and overall hormonal equilibrium.