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Methyl Donor Status

Meaning

The measure of the body’s available supply and utilization of essential biochemical compounds that can donate a methyl group (CH3) for critical metabolic and epigenetic reactions. Key methyl donors include S-adenosylmethionine (SAMe), folate, and Vitamin B12. Adequate status is crucial for DNA synthesis, detoxification pathways, neurotransmitter production, and the fundamental epigenetic process of DNA methylation.