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Metformin Response

Meaning

Metformin response describes the individual patient’s physiological and clinical reaction to the biguanide drug Metformin, primarily used to manage type 2 diabetes and insulin resistance. The response is measured by the degree of improvement in glycemic control, reduction in insulin levels, and mitigation of associated metabolic comorbidities, such as Polycystic Ovary Syndrome (PCOS). Variability in response is a key clinical consideration, often influenced by genetic factors and gut microbiome composition.