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Metal-Ion Catalyzed Oxidation

Meaning

Metal-ion catalyzed oxidation is a specific chemical reaction where trace amounts of transition metal ions, such as iron or copper, accelerate the degradation of biological molecules, including hormones, peptides, and lipids, through the generation of reactive oxygen species. This process is a significant contributor to oxidative stress within the body and is a major pathway for the chemical breakdown of therapeutic peptide formulations. Minimizing this reaction is essential for preserving the stability and biological activity of sensitive hormonal compounds.