A comprehensive set of evidence-based interventions, including dietary patterns, nutrient timing, and exercise modalities, specifically designed to modulate energy expenditure, substrate utilization, and hormonal balance. These strategies are tailored to enhance metabolic health, improve body composition, and address underlying insulin resistance or dyslipidemia. They represent a deliberate, structured approach to influencing cellular energy dynamics.
Origin
These strategies draw from the clinical and scientific fields of exercise physiology, endocrinology, and nutritional science, evolving from general public health advice to highly personalized, biomarker-driven protocols. They are rooted in the principles of energy balance and hormonal signaling.
Mechanism
Metabolic strategies function by directly influencing key metabolic hormones, such as insulin, leptin, and adiponectin, to improve cellular nutrient sensing and energy partitioning. Mechanisms often involve creating specific periods of energy deficit or surplus to upregulate or downregulate pathways like gluconeogenesis and lipolysis, thereby resetting the body’s metabolic set point.
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