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Metabolic State Transition

Meaning

Metabolic State Transition describes the dynamic, adaptive shift in the body’s primary fuel utilization pathways, moving rapidly and efficiently between catabolic and anabolic states, or between reliance on glucose, fat, or ketones for energy. This physiological adaptability, often scientifically termed metabolic flexibility, is a crucial indicator of optimal metabolic health and systemic resilience. A smooth transition ensures consistent energy availability, prevents detrimental energy crashes, and is vital for sustained physical and cognitive performance. Impaired transition capacity, or metabolic rigidity, is a core functional feature of insulin resistance and chronic metabolic dysfunction.