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Metabolic Sensitization

Meaning

Metabolic Sensitization is a physiological state or therapeutic goal characterized by an enhanced responsiveness of cells and tissues to key metabolic signals, particularly hormones like insulin, thyroid hormone, and leptin. Achieving this state means the body requires a lower concentration of a hormone to elicit a maximal or desired cellular response, improving overall efficiency and reducing the risk of resistance syndromes. Clinically, this is a core objective in optimizing hormonal health, leading to better glucose regulation, energy balance, and body composition outcomes. It signifies a restoration of healthy cellular communication.