Metabolic Rate Variance quantifies the degree of fluctuation observed in an individual’s basal or resting metabolic rate over sequential measurements, often indicating instability in underlying regulatory processes. Significant variance suggests the system is inefficiently allocating energy resources. We look for consistency in energy expenditure.
Origin
This concept is derived from thermophysiology and metabolic assessment, where a stable RMR is generally indicative of endocrine equilibrium, particularly thyroid hormone action. Variance serves as a quantifiable measure of physiological noise.
Mechanism
Fluctuations are frequently driven by instability in autonomic nervous system tone or shifts in the peripheral conversion of T4 to T3, which directly impacts mitochondrial efficiency and thermogenesis. Reducing this variance often correlates with successful abatement of systemic stress and inflammation.
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