Metabolic Light Pollution describes the detrimental physiological impact of inappropriate exposure to artificial light, particularly short-wavelength blue light, during the biological night, leading to acute and chronic disruption of metabolic homeostasis. This exposure is a significant environmental stressor that interferes with the time-dependent regulation of glucose, lipid, and energy metabolism. It is a modern contributor to metabolic dysfunction.
Origin
This term merges the environmental concept of ‘light pollution’ with the clinical domain of ‘metabolic’ health, highlighting the pervasive, non-visual consequence of nighttime light exposure. It emphasizes the disruptive influence on the body’s intrinsic biological timing.
Mechanism
Light exposure at night directly suppresses the nocturnal secretion of melatonin, a hormone with known anti-diabetic and metabolic regulatory properties. This disruption shifts the circadian clock, leading to mistimed insulin secretion and reduced glucose tolerance, a condition known as chronodisruption. The resultant desynchronization between the central pacemaker and peripheral metabolic clocks promotes insulin resistance and dyslipidemia.
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