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Metabolic Hormone Signaling

Meaning

Metabolic Hormone Signaling describes the intricate cellular communication network governed by hormones that regulate energy homeostasis, including glucose utilization, lipid storage, and satiety control. Key hormones in this network include insulin, leptin, ghrelin, and thyroid hormones, which coordinate the body’s response to nutrient intake and energy expenditure. Effective signaling is critical for maintaining healthy body weight, preventing insulin resistance, and ensuring proper fuel distribution to all tissues. Disruptions in this communication are central to the pathogenesis of metabolic syndrome and type 2 diabetes.