Metabolic Homeostasis Nighttime refers to the critical physiological state of balanced energy regulation, substrate utilization, and hormonal equilibrium that the body actively maintains during the sleep period. This state involves a coordinated shift toward parasympathetic dominance, favoring anabolic processes like tissue repair and fat oxidation over glucose utilization. Achieving robust nighttime metabolic homeostasis is essential for weight management, insulin sensitivity, and overall cellular restoration.
Origin
This concept is derived from metabolic physiology and sleep research, recognizing that the sleeping state is an active period of regulated metabolism, not merely a cessation of activity. The term emphasizes the body’s sophisticated, hormonally mediated effort to maintain stability during a prolonged fasting period. It links sleep quality directly to long-term metabolic health outcomes.
Mechanism
During sleep, the secretion of insulin decreases, while growth hormone and cortisol levels exhibit pulsatile release, coordinating cellular repair and gluconeogenesis to maintain stable blood glucose. A shift toward fat oxidation is facilitated by these hormonal changes, providing a steady energy supply. Disrupted sleep, however, can elevate evening cortisol and suppress growth hormone, leading to insulin resistance and a compromised ability to achieve this vital restorative metabolic state.
We use cookies to personalize content and marketing, and to analyze our traffic. This helps us maintain the quality of our free resources. manage your preferences below.
Detailed Cookie Preferences
This helps support our free resources through personalized marketing efforts and promotions.
Analytics cookies help us understand how visitors interact with our website, improving user experience and website performance.
Personalization cookies enable us to customize the content and features of our site based on your interactions, offering a more tailored experience.