A targeted, time-limited clinical intervention designed to rapidly improve markers of metabolic dysfunction, such as insulin resistance, dyslipidemia, and systemic inflammation, thereby re-sensitizing peripheral tissues to endogenous metabolic signals. It seeks a swift return to optimal energy handling.
Origin
Emerging from applied physiology and clinical nutrition, the “reset” implies a decisive break from chronic maladaptive metabolic patterns, similar to rebooting a malfunctioning computer system. It focuses on acute reversal of acquired deficits.
Mechanism
This reset often involves strategic manipulation of nutrient timing, caloric restriction, or specific macronutrient ratios to acutely lower circulating insulin levels and reduce hepatic glucose output. Such protocols enhance insulin receptor signaling efficiency, facilitating improved glucose uptake and fat oxidation.
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