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Metabolic Health Cognitive Decline

Meaning

Metabolic health cognitive decline is a specific form of intellectual deterioration directly linked to chronic dysregulation of systemic metabolism, most commonly involving insulin resistance, glucose intolerance, and dyslipidemia. This condition underscores the intimate and critical connection between metabolic homeostasis and neurological function. It is characterized by progressive deficits in memory, processing speed, and executive function, often preceding or co-occurring with overt metabolic diseases like Type 2 diabetes. Addressing the underlying metabolic dysfunction is a primary strategy for brain aging intervention.